signs

• Difficulty breathing or wheezing
• Swelling of face, lips, tongue, or throat
• Hives or widespread skin redness
• Rapid pulse or drop in blood pressure
• Dizziness, fainting, or loss of consciousness
• Severe nausea, vomiting, or diarrhea
• Feeling of impending doom

rule

When in doubt, use it. Epinephrine is safe and can save a life. It's better to use it unnecessarily than to delay treatment.

timing

Use immediately at first sign of severe reaction - don't wait

essential

All patients and caregivers must be trained on proper use

components

• How to recognize anaphylaxis
• How to use the specific device
• When to use epinephrine
• When to call 911
• How to give a second dose if needed

resources

• Training devices (practice injectors without needle)
• Video tutorials from manufacturer
• In-office training with healthcare provider
• Regular review and refresher training

practice

Practice with training device regularly to maintain confidence

location

• Keep with patient at all times
• Don't leave in car (temperature extremes)
• Keep in original case
• Have multiple devices (home, school, work, etc.)

expiration

• Check expiration dates regularly
• Replace before expiration
• Some devices have visual/audio expiration reminders

prescription

Requires prescription from healthcare provider

quantity

Prescribe 2-3 devices (one may be needed, second as backup)

insurance

Coverage varies - may need prior authorization

programs

Manufacturer assistance programs available for some patients

timing

Refill before expiration to ensure continuous availability

immediate

• Call 911 or go to emergency room immediately
• Even if symptoms improve, medical evaluation is needed
• May need second dose if symptoms return or worsen

medical

Seek emergency care even after using epinephrine - symptoms can return