Leukotriene Inhibitors
Sublingual Immunotherapy (SLIT) for indoor, outdoor, and food-related allergies
Targets the root cause of allergies by training your immune system over time
Convenient at-home treatment, shipped directly to you
Personalized formulas tailored to your specific allergy triggers
Clinician-guided care, prescribed and monitored by licensed Allergy Center providers
Starting at
$50/mo
Overview
Leukotriene inhibitors block the action of leukotrienes, chemicals that contribute to inflammation and constriction in allergic reactions and asthma. They're used as supportive therapy for certain allergy and asthma symptoms.
available
montelukast
brand
Singulair
uses
- Allergic rhinitis
- Asthma
- Exercise-induced bronchoconstriction
dosing
Once daily, usually in the evening
zafirlukast
brand
Accolate
uses
- Asthma
dosing
Twice daily
zileuton
brand
Zyflo
uses
- Asthma
dosing
Four times daily
note
Requires liver function monitoring
best For
- Allergies + asthma overlap
- Certain night-time symptoms
- Support when appropriate
- Exercise-induced asthma
- Patients who cannot tolerate or prefer alternatives to inhaled medications
effectiveness
asthma
Moderate effectiveness for asthma control, often used as add-on therapy
allergies
Some benefit for allergic rhinitis, but less effective than nasal steroids or antihistamines
combination
Often used in combination with other medications for comprehensive control
side Effects
common
- Headache
- Nausea or stomach upset
- Fatigue or drowsiness
rare
- Mood changes or behavioral changes (especially in children with montelukast)
- Liver problems (with zileuton)
- Allergic reactions
warnings
- Monitor for mood or behavioral changes, especially in children
- Report any unusual symptoms to healthcare provider
- Zileuton requires regular liver function monitoring
considerations
- Not a first-line treatment for allergic rhinitis
- More commonly used for asthma or asthma-allergy overlap
- May be helpful for exercise-induced symptoms
- Can be used in combination with other allergy medications
Ready to Get Started?
Schedule a consultation to discuss your specific needs and create a personalized treatment plan.