Nasal Sprays · Nasal corticosteroid
Mometasone (Nasonex): OTC Nasal Steroid Spray
Brand names: Nasonex
Last reviewed June 9, 2026 · Medically reviewed by AllergyCenter
Get Mometasone
Buy generic — OTC
Generic Mometasone Nasal Spray 50 mcg
120 metered sprays (1 bottle)
- Same active ingredient as the brand
- Free shipping (3–5 business days)
- No prescription needed
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Need a prescription?
Allergist Review — $49
For prescription strengths, combination products, or higher doses.
- Dymista (azelastine + fluticasone combo) for more complete relief
- Higher-potency nasal steroids or combination therapy
- Custom-compounded formulations for sensitive patients
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Mometasone — sold as Nasonex — is a nasal steroid spray that calms inflammation in the nose. It's a strong alternative to Flonase (fluticasone) for nasal congestion, runny nose, and itchy nose from allergies. Standard dose is 2 sprays in each nostril once daily.
Like other nasal steroids, mometasone works best with daily use. Most patients feel partial relief within 12 hours and reach full benefit after 1–2 weeks.
Quick Facts
- Generic name
- Mometasone furoate
- Brand names
- Nasonex, Nasonex 24HR
- Drug class
- Nasal corticosteroid
- Form
- Metered nasal spray
- OTC or Rx
- OTC in the US since 2024. Some pediatric or specialty formulations remain Rx.
- Typical adult dose
- 2 sprays in each nostril once daily
- Age range
- 2+
- Onset of action
- ~12 hours; full effect in 1–2 weeks of daily use
TL;DR — At a Glance
- ·Mometasone (Nasonex) is a once-daily nasal steroid spray for allergies.
- ·Same drug class as Flonase — strong option for nasal congestion.
- ·Standard adult dose: 2 sprays in each nostril once daily.
- ·Takes 12 hours to start and 1–2 weeks for full effect.
- ·Common side effects: nosebleeds, nasal dryness, headache.
Need a stronger combination?
For severe nasal allergies, an allergist can prescribe Dymista (azelastine + fluticasone) or add an antihistamine spray for more complete relief.
Medical Disclaimer: This guide is for educational purposes only and is not a substitute for medical advice, diagnosis, or treatment from a licensed healthcare provider. Do not start, stop, or change any medication without consulting a qualified provider.