Asthma Controllers · Leukotriene receptor antagonist
Montelukast (Singulair): Prescription Allergy + Asthma Pill
Brand names: Singulair
Last reviewed June 9, 2026 · Medically reviewed by AllergyCenter
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Montelukast — sold as Singulair — is a once-daily prescription pill used for asthma and allergic rhinitis. It blocks leukotrienes, chemicals involved in airway inflammation and constriction. It's often used as add-on therapy when inhalers or antihistamines alone aren't enough — and is particularly helpful for exercise-induced asthma symptoms.
Important: in 2020, the FDA added a boxed warning to montelukast about serious neuropsychiatric side effects, including mood changes and rare reports of suicidal thoughts. Discuss the risks and benefits with your provider before starting.
Quick Facts
- Generic name
- Montelukast sodium
- Brand names
- Singulair
- Drug class
- Leukotriene receptor antagonist (LTRA)
- Form
- Tablet, chewable, oral granules
- OTC or Rx
- Prescription only
- Typical adult dose
- 10 mg once daily in the evening
- Age range
- 6 months+ (dose by age)
- Onset of action
- Within 1 day; full effect within weeks
- FDA boxed warning
- Serious neuropsychiatric events (mood changes, agitation, suicidal thoughts) have been reported. Discuss risks with your provider.
TL;DR — At a Glance
- ·Montelukast (Singulair) is a once-daily prescription pill for asthma and allergic rhinitis.
- ·Standard adult dose: 10 mg in the evening.
- ·Often used as add-on therapy, especially for exercise-induced bronchoconstriction.
- ·Carries an FDA boxed warning for neuropsychiatric side effects (mood, behavior, sleep, rare suicidal thoughts).
- ·Other side effects: headache, stomach upset, upper respiratory infection.
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An allergist can review your asthma or allergy symptoms, discuss the risks and benefits of montelukast, and send the prescription to your pharmacy or ship it to you.
Medical Disclaimer: This guide is for educational purposes only and is not a substitute for medical advice, diagnosis, or treatment from a licensed healthcare provider. Do not start, stop, or change any medication without consulting a qualified provider.